White Widow - Hybrid
Category: Nugs | Posted on Sat, December, 7th 2013 by THCFinder
FDA-approved medical marijuana clinical trial gets underway next month for kids with epilepsy
Category: Medical Marijuana | Posted on Sat, December, 7th 2013 by THCFinder
A nationally renowned pediatric neurologist at Saint Barnabas has gotten FDA approval to study whether a cannabis-based drug could prevent seizures in children diagnosed with severe forms of epilepsy.
The development is sure to be watched closely in New Jersey, where a number of families whose children have Dravet syndrome, a potentially deadly form of epilepsy, say they cannot obtain yet a useful form of medicinal marijuana through the state Department of Health.
The U.S. Food and Drug Administration gave Orrin Devinsky, director of the New York University and Saint Barnabas Comprehensive Epilepsy Center, Roberta Cilio of the University of California - San Francisco's Neurology Department, and GW Pharmaceuticals of the United Kingdom permission to use the experimental drug, Epidiolex, to treat 125 children with seizure disorders for whom traditional medicines have failed.
Enrollment in the trial will begin next month, Devinsky said.
"I think this is a big step forward in the science of Cannabidiods," said Devinsky, referring to the spectrum of active ingredients in marijuana. "We will finally get some some data on epilepsy, and this should provide the basis to plan a randomized double-blind study."
The drug is a liquid form of pure cannabidiol, a non-psychoactive component of the cannabis plant that according to anecdotal reports has shown to reduce the frequency and intensity of seizures in children. The FDA's Nov. 15th approval also gives Epidiolex "orphan drug" status, providing GW full marketing rights to be the lone producer of the product for seven years, the company said in a statement.
Orphan diseases are rare, occurring in less than 200,000 of people in the nation. There are 5,440 documented cases of Dravet syndrome in the United States and 6,710 in Europe, although the actual number may be higher because the condition is under-diagnosed, according to a statement from the pharmaceutical company. The seizures can damage the brain, delay development and cause lifelong intellectual disabilities.
Read more: http://www.nj.com
Marijuana Use Causes Man Boobs?
Category: News | Posted on Sat, December, 7th 2013 by THCFinder
Pot-smoking dudes, beware: That joint you're toking may be causing your breasts to blossom.
In a post for CNN on Thursday, Detroit-based plastic surgeon Dr. Anthony Youn warned that marijuana use could be behind the development of man boobs, known in the medical world as "gynecomastia," because of the drug's effects on hormone levels.
"Gynecomastia is caused by a hormone imbalance between testosterone and estrogen," Youn wrote. "When the ratio between testosterone and estrogen tips in favor of estrogen, the body responds by creating excessive breast tissue. Hence, man boobs."
Animal studies, the physician explained, have shown that exposure to tetrahydrocannabinol (THC), the active component in cannabis, can result in a "decrease in testosterone levels, a reduction of testicular size and abnormalities in…sperm."
The jury is still out, however, as to how weed effects hormone levels in humans, though there is some evidence to suggest that pot users have lower testosterone levels than non-users and that heavy doses of the drug may delay the onset of puberty in young men.
There may not be any definitive evidence as yet linking marijuana use and man boobs, but Youn is hardly the first person to suggest a connection.
According to a recent Philly.com report on the topic, the medical community has suspected a link between pot and moobs for decades. However, due to the drug's status as an illicit substance, there hasn't been sufficient research to confirm these speculations.
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