Category: Medical Marijuana
| Posted on Tue, May, 24th 2016 by THCFinder
While doing research for an article being featured in print later this year, I’ve accumulated a nice little body of quotes and research regarding the brain, its chemistry and the methods through which cannabis interacts with it- specifically, how cannabis can inspire creativity and thought.
Quotes included are from the abstract and are not meant to stand alone as definitive statements about each study’s conclusions.
3 Studies That Show Cannabis Grows Brain Cells
“The endocannabinoid system has been implicated in the modulation of adult neurogenesis.
Here, we describe the effect of type 1 cannabinoid receptor (CB1R) activation on self-renewal, proliferation and neuronal differentiation in mouse neonatal subventricular zone (SVZ) stem/progenitor cell cultures.
Expression of CB1R was detected in SVZ-derived immature cells (Nestin-positive), neurons and astrocytes.
Stimulation of the CB1R … increased self-renewal of SVZ cells, as assessed by counting the number of secondary neurospheres … Moreover, … treatment for 48 h, increased proliferation …
Surprisingly, stimulation of CB1R … also promoted neuronal differentiation (without affecting glial differentiation), at 7 days, as shown by counting the number of NeuN-positive neurons in the cultures.
Moreover, by … a method that allows the functional evaluation of neuronal differentiation, we observed an increase in neuronal-like cells.
This proneurogenic effect was blocked when SVZ cells were co-incubated with … the CB1R antagonist AM 251, for 7 days, thus indicating that this effect involves CB1R activation.
In accordance with an effect on neuronal differentiation and maturation … also increased neurite growth …
Taken together, these results demonstrate that CB1R activation induces proliferation, self-renewal and neuronal differentiation from mouse neonatal SVZ cell cultures.”