FDA-approved medical marijuana clinical trial gets underway next month for kids with epilepsy
Category: Medical Marijuana | Posted on Sat, December, 7th 2013 by THCFinder
A nationally renowned pediatric neurologist at Saint Barnabas has gotten FDA approval to study whether a cannabis-based drug could prevent seizures in children diagnosed with severe forms of epilepsy.
The development is sure to be watched closely in New Jersey, where a number of families whose children have Dravet syndrome, a potentially deadly form of epilepsy, say they cannot obtain yet a useful form of medicinal marijuana through the state Department of Health.
The U.S. Food and Drug Administration gave Orrin Devinsky, director of the New York University and Saint Barnabas Comprehensive Epilepsy Center, Roberta Cilio of the University of California - San Francisco's Neurology Department, and GW Pharmaceuticals of the United Kingdom permission to use the experimental drug, Epidiolex, to treat 125 children with seizure disorders for whom traditional medicines have failed.
Enrollment in the trial will begin next month, Devinsky said.
"I think this is a big step forward in the science of Cannabidiods," said Devinsky, referring to the spectrum of active ingredients in marijuana. "We will finally get some some data on epilepsy, and this should provide the basis to plan a randomized double-blind study."
The drug is a liquid form of pure cannabidiol, a non-psychoactive component of the cannabis plant that according to anecdotal reports has shown to reduce the frequency and intensity of seizures in children. The FDA's Nov. 15th approval also gives Epidiolex "orphan drug" status, providing GW full marketing rights to be the lone producer of the product for seven years, the company said in a statement.
Orphan diseases are rare, occurring in less than 200,000 of people in the nation. There are 5,440 documented cases of Dravet syndrome in the United States and 6,710 in Europe, although the actual number may be higher because the condition is under-diagnosed, according to a statement from the pharmaceutical company. The seizures can damage the brain, delay development and cause lifelong intellectual disabilities.
Read more: http://www.nj.com
Marijuana Use Causes Man Boobs?
Category: News | Posted on Sat, December, 7th 2013 by THCFinder
Pot-smoking dudes, beware: That joint you're toking may be causing your breasts to blossom.
In a post for CNN on Thursday, Detroit-based plastic surgeon Dr. Anthony Youn warned that marijuana use could be behind the development of man boobs, known in the medical world as "gynecomastia," because of the drug's effects on hormone levels.
"Gynecomastia is caused by a hormone imbalance between testosterone and estrogen," Youn wrote. "When the ratio between testosterone and estrogen tips in favor of estrogen, the body responds by creating excessive breast tissue. Hence, man boobs."
Animal studies, the physician explained, have shown that exposure to tetrahydrocannabinol (THC), the active component in cannabis, can result in a "decrease in testosterone levels, a reduction of testicular size and abnormalities in…sperm."
The jury is still out, however, as to how weed effects hormone levels in humans, though there is some evidence to suggest that pot users have lower testosterone levels than non-users and that heavy doses of the drug may delay the onset of puberty in young men.
There may not be any definitive evidence as yet linking marijuana use and man boobs, but Youn is hardly the first person to suggest a connection.
According to a recent Philly.com report on the topic, the medical community has suspected a link between pot and moobs for decades. However, due to the drug's status as an illicit substance, there hasn't been sufficient research to confirm these speculations.
Why People Don't Believe In Cannabis
Category: Culture | Posted on Fri, December, 6th 2013 by THCFinder
Aside from the fact that people have been continuously brainwashed, medical marijuana is a very tough medicine to back up. It's getting easier, as more states want to make the plant legal. However, it's extremely difficult to prove the validity of medical marijuana if there aren't enough medical studies presented to make people believe that the plant is an amazing medicine and cure for many of the disease and illnesses that exist in the world today.
The media is a very powerful aspect of our society. Anti-cannabis propaganda has been blasted on TV, radio, and in magazines since the plant became illegal. Some are immune to the message that these ads portray, wile others aren't so lucky. They are totally susceptible to the messages that cannabis is a negative thing. Since they believe everything that they're told, the ability to accept that a negative may be a positive when used in the correct context. Another example of this is the swastika. While most associate that symbol with Nazi Germany, it has been used as a positive symbol for far longer. More specifically used by Hindu and Buddhist religions. The symbol literally translates in to "it is good". But since the symbol was adopted by such a negative party, it is always associated with negativity.
It is unfortunate that marijuana, like the swastika, is grouped in to this dark category. But without the ability to think for themselves, the people really don't know any better. With the plant being illegal, there is very little opportunity for medical studies to be conducted. Since medical institutions can't really research federally illegal substances, it's extremely difficult to get information about the benefits of cannabis. Thankfully, there is more information being gathered, studied, and released.
So between the fact that the majority of people are brainwashed and that marijuana has always been grouped as a negative thing (Besides the good old days where you had to grow hemp or it was punishable by law), people just don't believe. But as stated above, cannabis is beginning to make a serious splash. More studies means an easier time convincing the non-smokers that we're not just super stoned. We have medical studies, scientific studies, and enlightened minds. There should be no reason that people can deny the powers of cannabis.
- 186,127 Views Category: Odd
- 146,035 Views Category: Fun
- 136,134 Views Category: Culture
- 94,512 Views Category: Culture
- 94,020 Views Category: Fun
- 92,617 Views Category: Culture
- 74,984 Views Category: Culture
- 72,822 Views Category: Odd
- 65,090 Views Category: Fun
- 58,008 Views Category: Fun