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Move Over Mary Jane, UCI May Unlock The 'Bliss Molecule'

Category: News | Posted on Mon, November, 28th 2011 by THCFinder
No inhaling necessary—your brain produces a marijuana-like chemical with the ability to reduce pain, anxiety, and depression, and scientists are uncovering more about how this neurotransmitter works.
 
Sometimes called “the bliss molecule,” the brain chemical anandamide is one of the compounds produced by the endocannabinoid system. These compounds are very similar to the active ingredient in marijuana, THC.
 
A new study by UC Irvine researchers reveals that a protein in the brain ferries anandamide to sites in brain cells where enzymes break down and inactivate the “bliss” chemical. The study, published in Nature Neuroscience, shows that blocking this protein increases the potency of anandamide, and may unlock new possibilities in pain control.
 
The revelation about anandamide transport and breakdown opens up the potential to develop pain medications that don’t produce sedation, addiction, or other central nervous system effects associated with opiates, which are often used to control severe and chronic pain.
 
UCI professor of pharmacology Daniele Piomelli led the team that interpreted how the protein, called FLAT, binds with anandamide and escorts it to cell sites where it is broken down by fatty acid amide hydrolase, or FAAH, enzymes. This process inactivates the “bliss” effect of anandamide.
 
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The Price is right bitch!

Category: Fun | Posted on Mon, November, 28th 2011 by THCFinder

420 for the win!

 

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Miley Cyrus admits shes a stoner!

Category: Celebrities | Posted on Mon, November, 28th 2011 by THCFinder
HollywoodNews.com: Miley Cyrus’ rep is doing some clean up as the young star recently commented during her birthday that she is a “stoner.”
 
Her rep is now commenting that the birthday matter was all a simple joke, states UsMagazine.com. “It’s all been taken out of context. The cake was a joke and Miley’s response was intended to be sarcastic,” her rep commented.
 
Miley reportedly received a Bob Marley cake and commented, “You know you’re a stoner when your friends make you a Bob Marley cake. You know you smoke way too much f-cking weed!”
 
Miley did get in some hot water back when she was caught on tape supposedly smoking salvia.
 
Do you think it was all a joke?
 
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Super dank

Category: Fun | Posted on Mon, November, 28th 2011 by THCFinder

When your weed is that good...

 

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There's DNA in that weed you're smoking, and people are tracking it

Category: News | Posted on Mon, November, 28th 2011 by THCFinder
Warning: The dope you are smoking can now be identified by its DNA.
 
Heather Coyle’s new marijuana DNA database at the University of New Haven can tell if a particular fragment of pot is the “White Widow” strain, “Skunk Number One,” “Super Silver Haze” or another of the more than 25 types of marijuana that she’s genetically mapped.
 
The DNA analysis can let cops and federal agents trace the marijuana from a single bud or seed found in Connecticut back to its source, as long as they can get ahold of samples to match.
 
They can find out whether it was grown in Mexico and formed part of a drug cartel’s shipment. Or maybe the dope was part of a crop from northern California’s “Emerald Triangle” and sold at a freewheeling Los Angeles medical marijuana dispensary.
 
Coyle says this system of genetic fingerprinting could also be used to offer states a foolproof way to control and regulate medical pot programs.
 
And it just so happens that Connecticut officials are right now wondering about exactly that sort of issue as they consider passing a medical marijuana law here.
 
Coyle is a 46-year-old “forensic botanist” and an associate professor at UNH since 2005. Before arriving at the university, she spent seven years working at the Connecticut state forensics lab in Meriden.
 
A forensic botanist helps cops solve cases by identifying and analyzing samples of plants taken from crime scenes. If this sounds like the cool shit that happens in TV crime dramas, you’re exactly right. It’s not much of a surprise to learn that Coyle is a fan of those shows.
 
“’NCIS’ is one of my favorites,” she says, smiling.
 
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Corona Bong

Category: Fun | Posted on Sun, November, 27th 2011 by THCFinder

The best of both worlds!

 

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