Study: THC Reduces Methamphetamine-Induced Brain Damage
Category: Medical Marijuana | Posted on Tue, May, 27th 2014 by THCFinder
A new study published in this month’s issue of the journal PLoS ONE, and published online by the National Institute of Health, has found that THC (Δ9-tetrahydrocannabinol) can reduce and even prevent brain damage caused by methamphetamine intake.
According to the study, titled Δ9-tetrahydrocannabinol prevents methamphetamine-induced neurotoxicity, “Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic effects.”
It continues; “Preclinical studies have shown that natural (Δ9-tetrahydrocannabinol, Δ9-THC) and synthetic cannabinoid CB1 and CB2 receptor agonists exert neuroprotective effects on different models of cerebral damage. Here, we investigated the neuroprotective effect of Δ9-THC on METH-induced neurotoxicity by examining its ability to reduce astrocyte activation and nNOS overexpression in selected brain areas.”
Using rat models, researchers discovered that; “Our results indicate that Δ9-THC reduces METH-induced brain damage via inhibition of nNOS expression and astrocyte activation through CB1-dependent and independent mechanisms, respectively.”
Read more: http://www.theweedblog.com
Cold Creek Kush
Category: Nugs | Posted on Tue, May, 27th 2014 by THCFinder
Why Children Deserve Cannabis
Category: Culture | Posted on Tue, May, 27th 2014 by THCFinder
While giving kids cannabis for health issues isn't exactly common practice, it's these young people who need the plant more than anyone when they're suffering from epilepsy or cancer. The medicines that are produced by large pharmacy can have dangerous side effects, not to mention the rapid deteriorating effect that chemo has on a person. Kids especially need the healing power of cannabis because it virtually has no side effects, leaving the young one using it to develop and live a more normal childhood.
When a person is diagnosed with epilepsy, it means that the neurotransmitters in the brain are constantly firing. These transmitters are part of the encocannabinoid system that every human body possesses and are also connected to the psychoactive effects of THC. However, when high levels of CBD are introduced, it triggers a reaction in the endocannabinoid system and sends messages to the transmitters, telling them to stop firing off so rapidly. This effect drastically decreases seizing in patients and is being looked at as an incredibly effective medicine against epilepsy, especially in children.
CBD treatments on children with epilepsy were shown to be incredibly effective. Parents of these children were so happy with the results that they claimed the plant to be an actual miracle... Which, after trying multiple different pills, tranquilizers, and steroids, isn't a surprise. A study done by the National Institute of Health in 2013 showed that CBD treatments in children with epilepsy showed that 16 out of 19 children taking CBD showed drastic improvement. In two of those cases, the epilepsy disappeared completely.
The appeal of highly concentrated CBD cannabis products is overwhelming. Even though there are some people who still don't agree (there are many reports of families getting Child Protective Services called on them for using cannabis as a treatment rather then the "normal" way), the progress of the children who are taking cannabis now cannot be denied. Pills given to these kids can cause liver failure, developmental problems, and completely take away the child's lust for life, causing them to become zombified and sad. A child should not have to spend their younger years in hospitals or being shot up with terrible drugs with adverse effects. If there is a natural, side effect free cure out there, there's absolutely no reason why we shouldn't be using it, researching it, and benefiting from it.
Hundreds of families have relocated to the state of Colorado in order to get their hands on the strain of cannabis known as Charlotte's Web, named after a little girl with epilepsy that the strain was specifically made for. The stain contains only the very smallest amounts of THC, leaving almost no psychoactive effect when ingested. Instead, the strain has an extremely high CBD content. The waiting list for this particular strain is months long and full of hopeful parents that want nothing but health for their suffering children.
Uruguay To Sell Recreational Marijuana Tax Free
Category: Legalization | Posted on Mon, May, 26th 2014 by THCFinder
Uruguay recently became the first country to completely legalize cannabis, and has big plans to create a recreational marijuana industry. This has lead to numerous other countries considering following suit. I think after other countries see how well it works, it will speed up the process of reform around the world. Hopefully the United States gets on that bandwagon sooner than later at the federal level.
A lot of people in the media and in the international community were shocked to see Uruguay make such a bold move. But I think the most shock came from the United States cannabis industry when it became known that Uruguay would be selling cannabis at such a low price – less than one dollar per gram. That price is considerably lower than prices in stores in Colorado.
It appears that Uruguay will be making another bold move with their cannabis policy – selling legal recreational cannabis tax free. Per Reuters:
Uruguay will exempt marijuana production and sales from taxes in a bid to ensure prices remain low enough to undercut competition from black market pot smuggled in from Paraguay, according to consultants advising the government on a legalization plan.
“The principal objective is not tax collection. Everything has to be geared toward undercutting the black market,” said Felix Abadi, a contractor who is developing Uruguay’s marijuana tax structure. “So we have to make sure the price is low.”
Uruguay will auction up to six licenses to produce cannabis legally in the next weeks. The government is also considering growing marijuana on a plot of land controlled by the military to avoid illegal trafficking of the crop.
One of the biggest selling points in the United States to reform cannabis laws and allow the industry to operate is that it will generate a significant amount of tax revenue. It seems that Uruguay is not as concerned with generating tax revenue. I think legalization combined with extremely low prices will catapult Uruguay to the status of ‘most cannabis friendly destination’ once sales start rolling out. How Uruguay will deal with an influx of foreign travelers is yet to be seen, but I think added tourism is ‘problem’ every nation would love to have.
Laura Blanco, President of Uruguay’s Cannabis Studies Association will be on hand at our conference in September to give attendees a first-hand account from the country making international waves by regulating cannabis sales. Join us in Portland, Oregon, as we bring together entrepreneurs, activists and professionals from across the globe to provide an international cannabis conference like no other.
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