Scientists Found a Compound That Keeps Marijuana From Getting You High
Category: News | Posted on Wed, October, 16th 2013 by THCFinder
Tetrahydrocannabinol, or THC, is the dopamine-boosting compound in marijuana that, technically speaking, "induces euphoria" — science jargon for "gets you high." It also happens to work on the brain region involved in psychological addiction. Now, a team of researchers has identified a substance that blocks THC's dopamine effect. Why is that important? Let's have a grown-up discussion about weed.
We've already written about the mechanics behind how marijuana makes you feel. But you may be surprised to find out that in the United States, over a million people sought treatment for marijuana dependence in 2009 (Figure 7.8), nearly as many as did for cocaine and heroin combined. While the Marijuana Policy Project points out that 57% of those receiving treatment in the U.S. did so in lieu of serving a prison sentence, people still seek anti-dependence treatment in countries like the Netherlands where marijuana use has been decriminalized.
Like most drugs with addictive potential, THC works by increasing dopamine levels in the "reward centers" of the brain (the ventral tegmental area and the nucleus accumbens). A team led by researchers at the University of Maryland School of Medicine and the National Institute on Drug abuse found that the drug Ro 61-8048 blocks THC's ability to stimulate dopamine production in the brain's reward centers. Without dopamine, there's no neurological reward to the drug, and no drive to continue using it.
The researchers taught squirrel monkeys to self-administer THC by pushing a lever. Once the monkeys exhibited signs of addiction (in this case, frequent lever pushing), Ro 61-8048 reduced the reward effect of continual THC doses, leading the monkeys to stop seeking additional doses. The same behavior was seen in rats that were taught to dose themselves with WIN 55,212-2, a synthetic THC substitute.
Read more: http://gizmodo.com
White Diamond Cannabis
Category: Nugs | Posted on Wed, October, 16th 2013 by THCFinder
Denvers anti-marijuana-smell proposal nearly snuffed out
Category: News | Posted on Wed, October, 16th 2013 by THCFinder
The proposed city ordinance in Denver that would re-criminalize possession of marijuana in some public places and impose a year in jail and $999 fine for marijuana smell got what seemed to be a pretty cool reception today.
A council committee there took up the ordinance, beat it up and promised to revisit it, likely significantly redrafted, sometime down the road.
What’s it matter to Seattle/Washington and The Pot Blog?
The proposed rules came about as backlash to open use of marijuana in the city and lingering concerns about the social issues legal pot brings up: How kids will perceive marijuana use, whether its use will degrade the business climate downtown and if people will have to live with the smell of pot the next time they throw a birthday party for their kid in a park …
Consequently, it seems prudent to expect efforts to curtail marijuana use here as the legal system comes on board, the legal marijuana market gets underway and people see and smell it more.
Read more: http://blog.seattlepi.com
Vicious OG - Indica
Category: Nugs | Posted on Tue, October, 15th 2013 by THCFinder
Weed Prices Affect Amount Of Medicine For Patients Everywhere
Category: Medical Marijuana | Posted on Tue, October, 15th 2013 by THCFinder
Since every state is in a different place in the process of growing the best bud, those who smoke suffer at the mercy of the place where they get their weed. With prices all over varying from the rock bottom price of $25 an eighth to $90 for the same amount. The average cost of 3.5 grams seems to be somewhere around $55. Paying for weed is kind of a bummer at all, considering it's a plant and anyone should be allowed to grow it.
A lot of stoners say that the price of their bud is a huge impact on the amount they're smoke. Let's face it, before we're smokers, we have to be responsible adults. Bills and food come before weed (hopefully) so there are a lot of people who don't get enough of the medicine they need. They can't afford it. It's also a matter of who you know in your state. A friend that sells bud is sure to hook up his closest buddies before those that he doesn't really hang out with.
Of course, for those in illegal states, it's much worse. Since the risk of growing is so much higher, the weed must be transported in. This effects cost greatly because transporting marijuana across state lines is a serious offense. States such as certain areas of New Jersey, where the price of 3.5 grams is $90, the marijuana market is cripplingly expensive. The weed is barely affordable and stoners must cut back drastically. With high prices like this, it's sad to say that smoking would have to take a backseat for most people, especially in this economy.
In the legal states, the prices are as low as $25 for an eighth. Not only that but patients are allowed to grow their. A lot of smokers out there don't even need to pay for weed, just pay attention to their plants. While growing is difficult, it begins to save you large amounts of money, especially if you're buying a $50 eighth every few days and your weed smoking costs you $400 a month. When you think about it that way, it makes more sense to grow your own. Then, you know where the bud is coming from and you can grow whatever strain you want. In some places, $400 a month is rent or at least most of the other bills that stoners pay.
We can only hope that someday, all of our bud prices will be somewhere around the same. Preferably the $25 amount that some people enjoy. Unfortunately for now, a lot of us will have to continue to pay somewhere around $50 for an eighth of bud. Being able to afford bud is definitely a problem for a lot of patients that are still living in illegal states. The push for legalization will hopefully reach the states with the most expensive bud soon, so that patients will be able to get what they need.
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