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White Fire Cannabis

Category: Nugs | Posted on Wed, July, 17th 2013 by THCFinder

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Watch Grinders

Category: Fun | Posted on Wed, July, 17th 2013 by THCFinder

grind-buds-with-watches


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Patient advocates ask Supreme Court to decide medical value of marijuana

Category: Medical Marijuana | Posted on Wed, July, 17th 2013 by THCFinder
The U.S. Supreme Court has the opportunity to lift federal restrictions on marijuana. A group that advocates on behalf of medical marijuana patients has asked the nation’s highest court to decide whether marijuana is a dangerous drug with no medical value.
 
Americans for Safe Access on Monday appealed a District of Columbia Circuit Court decision that upheld marijuana’s federal Schedule I status.
 
“It is only by failing to apply the appropriate standards and make the required comparisons that the federal government could conclude that marijuana is as harmful as heroin and PCP and even more harmful than methamphetamine, cocaine and opium, and should remain in the CSA’s most restrictive Schedule I,” the appeal states (PDF).
 
The D.C. Circuit ruled in January that the Drug Enforcement Agency could continue to classify the marijuana plant a Schedule I drug, a classification reserved drugs with no medical value and a high potential for abuse. Though ASA cited more than 200 peer-reviewed studies on marijuana’s medical benefits, the court held the drug could not be reclassified without FDA-approved Phase II and Phase III clinical trials.
 
In their appeal, ASA contends the D.C. Circuit Court was wrong to equate “currently accepted medical use” with only FDA-approved studies. The D.C. Circuit Court also “simply ignored that marijuana has an extremely low abuse potential relative to other controlled substances, despite having been presented voluminous evidence,” according to the appeal.
 

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Tahoe OG MMJ

Category: Nugs | Posted on Wed, July, 17th 2013 by THCFinder

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New Study: Cannabis Can Slow, Cure Alzheimers Disease

Category: Medical Marijuana | Posted on Wed, July, 17th 2013 by THCFinder
curing-ailments
 
A new study conducted by researchers at the Roskamp Institute in Florida, and published in the journal Molecular and Cellular Neuroscience, has found that cannabis can slow the effects of Alzheimer’s Disease, and may in fact be able to halt it entirely.
 
According to Corbin Bachmeier, Ph.D – who’s the lead researcher of the study – Alzheimer’s Disease is “the result of impaired Aβ [Amyloid-β protein] clearance from the brain”. According to this study, cannabis can solve this problem, making it a potential treatment.
 
Here’s the study’s abstract:
 
Emerging evidence suggests beta-amyloid (Aβ) deposition in the Alzheimer’s disease (AD) brain is the result of impaired clearance, due in part to diminished Aβ transport across the blood-brain barrier (BBB). Recently, modulation of the cannabinoid system was shown to reduce Aβ brain levels and improve cognitive behavior in AD animal models. The purpose of the current studies was to investigate the role of the cannabinoid system in the clearance of Aβ across the BBB. Using in vitro and in vivomodels of BBB clearance, Aβ transit across the BBB was examined in the presence of cannabinoid receptor agonists and inhibitors. In addition, expression levels of the Aβ transport protein, lipoprotein receptor-related protein1 (LRP1), were determined in the brain and plasma of mice following cannabinoid treatment. Cannabinoid receptor agonism or inhibition of endocannabinoid-degrading enzymes significantly enhanced Aβ clearance across the BBB (2-fold). Moreover, cannabinoid receptor inhibition negated the stimulatory influence of cannabinoid treatment on Aβ BBB clearance. Additionally, LRP1 levels in the brain and plasma were elevated following cannabinoid treatment (1.5-fold), providing rationale for the observed increase in Aβ transit from the brain to the periphery. The current studies demonstrate, for the first time, a role for the cannabinoid system in the transit of Aβ across the BBB. These findings provide insight into the mechanism by which cannabinoid treatment reduces Aβ burden in the AD brain and offer additional evidence on the utility of this pathway as a treatment for AD.
 
This research validates past studies (including some presented earlier this year, as well as a 2006 study), though is the first to actually explain why cannabis can be beneficial to the disease.
 

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U2 OG

Category: Nugs | Posted on Tue, July, 16th 2013 by THCFinder

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