VSOG - Very Special OG (Sativa)
Category: Nugs | Posted on Tue, November, 26th 2013 by THCFinder
Study shows marijuana's potential for treating autoimmune disorders
Category: Medical Marijuana | Posted on Tue, November, 26th 2013 by THCFinder
A new study from researchers at the University of South Carolina provides evidence that THC (tetrahydrocannabinol), a principal ingredient in marijuana, may be beneficial in treating those with autoimmune disorders.
The study, published in the Journal of Biological Chemistry, is the first to explore how tiny, yet powerful molecules called microRNAs are influenced by THC. MicroRNAs are a recently discovered class of non-coding RNAs that play a pivotal role in the regulation of gene expression. The ability to alter microRNA expression could hold the key to successful treatments for a whole host of autoimmune diseases, including arthritis, multiple sclerosis and type 1 diabetes.
The study was performed by researchers from USC's School of Medicine by injecting laboratory mice with THC and analyzing 609 microRNAs. The researchers identified 13 unique microRNAs that were highly altered by THC.
MicroRNAs have profound effects on the immune system, acting as 'brakes' that target more than 60 percent of all gene expression. Since microRNAs normally suppress the expression of genes, when a microRNA is overexpressed, the affected gene gets silenced. But when microRNA is turned off, the affected gene is expressed at an elevated level.
The authors also studied how a specific microRNA—miRNA-690—that was highly overexpressed in response to THC functionally targets an important protein called C/EBPα. This molecule in turn triggers unique cells known as MDSC that suppress inflammation. When the researchers successfully knocked down miRNA-690, the effect of THC was reversed.
Read more: http://medicalxpress.com
More drivers test positive for pot since Washington legalized cannabis
Category: News | Posted on Tue, November, 26th 2013 by THCFinder
The number of Washingtonians who tested positive for pot while driving got higher ever since the leaf's legalization in January, authorities said.
Washington State Patrol says it found THC, marijuana's psychoactive ingredient, in the bloodstream of 745 drivers pulled over this year.
That’s a nine percentage point increase from where we were last year at this time, Sgt. Jason Hicks explained.
"It was previously illegal to drive under the influence of marijuana and it remains illegal," Mason Tvert, spokesperson for the Marijuana Policy Project (MPP), told the Daily News.
"Law enforcement officials should focus their time and attention on people driving impaired on any substance and not just possessing marijuana."
MPP's goal is to end marijuana prohibition and replace it with a system where marijuana is regulated like alcohol.
And like alcohol, testing positive for pot does not necessarily mean that the driver is impaired. The legal limit is 5 nanograms of THC per milliliter of blood.
But 420 of those 745 who tested positive exceeded that limit.
Read more: http://www.nydailynews.com
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