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Category: Fun | Posted on Mon, September, 9th 2013 by THCFinder



New Study Finds Marijuana Could Help Treat Alzheimers Disease

Category: Medical Marijuana | Posted on Mon, September, 9th 2013 by THCFinder
cannabis-fights-Alzheimers-diseaseA new study published by the journal Neurobiology of Aging has found that marijuana might actually help treat Alzheimer’s disease.
Based on a series of experiments with mice, researchers believe that they have evidence which shows that Alzheimer’s disease is worsened by a deficiency in the body’s cannabinoid receptors, indicating that the disease could be treated with cannabis.
According to the study’s abstract:
Alzheimer's disease (AD) is characterized by amyloid-β deposition in amyloid plaques, neurofibrillary tangles, inflammation, neuronal loss, and cognitive deficits. Cannabinoids display neuromodulatory and neuroprotective effects and affect memory acquisition. Here, we studied the impact of cannabinoid receptor type 1 (CB1) deficiency on the development of AD pathology by breeding amyloid precursor protein (APP) Swedish mutant mice (APP23), an AD animal model, with CB1-deficient mice. In addition to the lower body weight of APP23/CB1−/− mice, most of these mice died at an age before typical AD-associated changes become apparent.
The surviving mice showed a reduced amount of APP and its fragments suggesting a regulatory influence of CB1 on APP processing, which was confirmed by modulating CB1 expression in vitro. Reduced APP levels were accompanied by a reduced plaque load and less inflammation in APP23/CB1−/− mice. Nevertheless, compared to APP23 mice with an intact CB1, APP23/CB1−/− mice showed impaired learning and memory deficits. These data argue against a direct correlation of amyloid plaque load with cognitive abilities in this AD mouse model lacking CB1


Larry OG Weed

Category: Nugs | Posted on Mon, September, 9th 2013 by THCFinder


Measure To Legalize Medical Marijuana Filed In Puerto Rico

Category: Legalization | Posted on Mon, September, 9th 2013 by THCFinder
puerto-rico-mj-legalizationLawmakers in Puerto Rico have filed a proposal aimed at legalizing the medicinal use of marijuana; the measure will be debated by the legislature in the coming days and weeks.
The measure – which is sponsored by State Reps. Jose Baez and Carlos Vargas – would allow authorized patients to possess cannabis, and purchase it through state-licensed clinics. Patients who can’t afford to purchase their medicine through clinics could apply for a special permit to cultivate their own cannabis at home.
“Treating this strictly as something that should be punished has clearly not worked,” says Representative Vargas.
Earlier this year a proposal was filed in Puerto Rico to legalize cannabis for recreational purposes; the bill, although it started an important conversation, never advanced, and currently sits in committee.
This new proposal, which is strictly for medical purposes, is something that advocates believe lawmakers will be much more willing to accept.
Those in Puerto Rico who support medical cannabis legalization should be contacting their lawmakers, urging them to support this new proposal.



Category: Nugs | Posted on Sun, September, 8th 2013 by THCFinder


Medical marijuana used for childs epilepsy

Category: Medical Marijuana | Posted on Sun, September, 8th 2013 by THCFinder
3yearold-given-medical-cannabisMARTINSBURG - Even though she's far from home, there's no mistaking the determination in Tara White's voice.
She talks via cellphone about how the use of medical marijuana could help her chronically ill, nearly 3-year-old son Brandon, who suffers from a rare type of epilepsy, why it means so much to his quality of life, and how much she's willing to do to help him feel better.
Local residents, the mother-son duo have been in Denver, Colo., for a month and have just achieved their medical marijuana goal, White said, adding that the final doctor's recommendation was given Wednesday.
Since being approved, the youngster - who will celebrate his third birthday Sept. 18 - received a brownish liquid that will hopefully meet his medical needs. It still contains the compound in marijuana - cannabiodiol (CBD) - that has positive medical effects, but lower levels of tetrahydrocannabinol (TCH) which is associated with the being "stoned," she said, adding that there's also some evidence that CBD can help counter the effects of TCH.
Although excited, White was also nervous about getting her son started on the medicine. She said the dosage will gradually increase as doctors evaluate his reaction - and, hopefully, progress.



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