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Medical Marijuana

Compounds In Cannabis Found To Reduce Nausea In New Study

Category: Medical Marijuana | Posted on Tue, September, 3rd 2013 by THCFinder
cannabis-naseuA new study published by the British Journal of Pharmacology and the National Institute of Health has found that THCV, and CBDV - two compounds found naturally in cannabis which aren’t psychoactive like THC – were both successful at reducing nausea in rat subjects.
 
For the study, researchers “evaluated two phytocannabinoids, cannabidivarin (CBDV) and Δ9 -tetrahydrocannabivarin (THCV) for their ability to produce these behavioural effects characteristic of CB1 receptor inverse agonism in rats.”
 
In doing so, researchers found that; “THC (2.5 and 10 mg kg-1 ), THCV (10 mg kg-1) and CBDV (200 mg kg-1 ) suppressed LiCl-induced conditioned gaping, suggesting anti-nausea potential.”
 
The study concludes; “The pattern of findings indicates that neither THCV nor CBDV produced a behavioural profile characteristic of CB1 receptor inverse agonists. As well, these compounds may have therapeutic potential in reducing nausea.”
 
This study indicates that it may be possible to use THCV or CBDV to help reduce nausea without bringing forth the psychoactive effects associated which THC, which may be seen as undesirable to some.
 
This research was funded in part by the Natural Sciences and Engineering Research Council of Canada.
 

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Marijuana Helps Reduce Cancer Pain

Category: Medical Marijuana | Posted on Tue, September, 3rd 2013 by THCFinder
cannabis-helps-reduce-cancer-painThe use of medical marijuana to treat pain and other symptoms associated with cancer and chemotherapy shows promising results, according to Israeli researchers who say many patients found they needed fewer painkillers.
 
In an eight week study of 131 cancer patients who used cannabis, published in the journal Evidence-Based Complementary and Alternative Medicine, researchers reported significant improvement across a range of symptoms.
 
All cancer or anti-cancer treatment-related symptoms, including nausea, vomiting, mood disorders, fatigue, weight loss, anorexia, constipation, sexual function, sleep disorders, itching, and pain had significant improvement,” wrote lead author Gil Bar-Sela, of the Integrated Oncology and Palliative Care Unit, Rambam Health Care Campus in Haifa.
 
“The population of the prolonged users in the current study reported significant improvement in all aspects of supportive and palliative oncology care.”
 
What makes this small study unique is its emphasis on medical marijuana, as opposed to synthetic cannabis, which is what researchers say is usually used during clinical studies.
 
Nearly one in three patients who used medical marijuana reported significant relief from cancer related pain and discomfort.
 
Of the 70 patients who used opioid pain medications at the start of the study, 31 of them reduced the dose they were taking eight weeks later.  One out of three patients taking anti-depressant or anxiety drugs also reported a reduction in dosage at the study’s end.
 

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Mormon mom wants medical marijuana for her sick son

Category: Medical Marijuana | Posted on Mon, September, 2nd 2013 by THCFinder
mormon-mom-wants-cannbisPleasant Grove • Jennifer May has tried 25 treatments in 10 years, a mix of prescribed diets and drugs, to quiet the lightning in her son's brain.
 
Only two eased Stockton May's seizures. But their toxic side effects ravaged his bones and immune system, and the relief was temporary.
 
His rare and intractable form of epilepsy, Dravet syndrome, "always found a way around the treatment," said his mom, a self-described conservative and devout Mormon who is now pursuing what for her was once unthinkable: medical marijuana.
 
Use of marijuana is outlawed in Utah. But mounting evidence of its medicinal benefits — from controlling cancer pain and nausea to reducing seizures — has pushed 18 states to legalize it for medical use.
 
Moved by preliminary studies and patient testimonials, May is now fighting for legislation to make it available to Utahns, including children with epilepsy.
 
"It's not just anecdotal. It's huge," she said. "We're talking about a group of kids for whom no other options are left."
 
She has the backing of the Epilepsy Association of Utah and a Facebook group of 25 to 30 like-minded moms.
 
"This is not smoking the drug, or getting high off it," she said, stressing she seeks only to legalize medical-grade products derived from the cannabis plant, and only for certain patients where science warrants it.
 
Utah's Republican legislative leaders have opposed any attempts to decriminalize marijuana, including pro-tem Senate President Curtis Bramble, R-Provo.
 
"If someone comes forward with credible research, I'll listen; I'll listen intently," he said Tuesday. "I'm not persuaded at this point."
 
But former Utah Attorney General Mark Shurtleff, a cancer survivor, has said he'd testify in favor of the drug's medical use.
 
Under current Utah law, possession of less than an ounce of marijuana can lead to a sentence of six months in jail and a $1,000 fine. The sale of any amount can result in a five-year sentence and a $5,000 fine.
 

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5-Year-Old Boy to Become Arizona's 40th Medical-Marijuana Patient Under the Age of 18

Category: Medical Marijuana | Posted on Sat, August, 31st 2013 by THCFinder
arizona-mmj-patientA 5-year-old Mesa boy will be Arizona's 40th medical-marijuana patient under the age of 18.
 
Zander Welton has cortical dysplasia, a brain abnormality, which causes him to have seizures, which several medications, two brain surgeries, and an implant haven't solved, according to his parents.
 
According to a fundtraising website set up by Zander's parents, one medication he's on helps decrease the seizures, but causes behavioral issues. The other option presented to them is "another brain surgery that separated the halves of his brain, which would have a 50% chance of reducing seizures, while including side effects like paralysis, coma, or a vegetative state."
 
His parents are now willing to try medical marijuana for their son.
 
ABC 15 recently did a segment on Welton, and stated that his medical-marijuana application has been accepted.
 
Zander's parents have also set up a Facebook page that chronicles Zander's struggles, including videos of him suffering seizures:
 
In the ABC 15 report, Zander's parents say that they saw videos online of other kids with similar medical issues doing extraordinarily well with medical-marijuana treatments.
 
The boy's parents have also set up a fundraising website, hoping to raise enough money to pay for a year of medical-marijuana treatments, which have been recommended by a doctor.
 
State health department statistics indicate that one-tenth of one percent of medical-marijuana cardholders are under the age of 18.
 

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Over 100,000 NYC Residents Could Benefit From Access To Medical Cannabis

Category: Medical Marijuana | Posted on Sat, August, 31st 2013 by THCFinder
nyc-medical-mj-patientsMore than 100,000 New York City residents suffering from serious medical conditions such as cancer and chronic pain could benefit from legal access to cannabis therapy, according to a report released today by the New York City Comptroller’s Office. The mission of the Comptroller’s Office is to ensure the financial health of New York City by advising the Mayor, the City Council, and the public of the City’s financial condition.
 
The report, entitled “100,000 Reasons: Medical Marijuana in the Big Apple,” finds that some 8 out of 10 New Yorkers endorse permitting patient access to medical cannabis, and estimates that at least 100,000 City residents would immediately benefit from its legalization.
 
“[W]e believe this is a conservative estimate,” authors of the report state, “because registration for medical marijuana programs in the various states falls short of the potential. Patients experience social stigma and related social sanctions for using medical marijuana, and many doctors are not familiar with its benefits. Moreover, the federal government has created unnecessary obstacles for academic and research institutions to study marijuana, thereby impeding research that could lead to a broader use of medical marijuana.”
 
The report endorses various legal and legislative efforts to amend state and federal marijuana laws. Locally, the report’s authors recommend that New York City establish a ‘Medical Cannabis Research Fund’ to engage in clinical study of the plant; they further proposes the establishment of cannabis grow operations at selected public hospitals. The report also recommends that health insurance providers be required cover some costs related to medical cannabis expenses.
 
“In the 1980s, New York State acknowledged marijuana’s medicinal value and supported research for chemotherapy patients,” the report concludes. “Even though the findings were impressive, the State stopped there. Thirty years later, New York still denies seriously ill patients access to this evidence-based treatment, even as 20 states and Washington D.C. have legalized it. … Today, at least 100,000 New York City residents with the same afflictions could benefit from the same relief. By following the recommendations outlined in this report, we can hit the ground running where we left off just 30 years ago and make a meaningful impact for New Yorkers suffering today and for years to come.”
 

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Harvard Study Finds Cannabis Cuts Tumor Growth In Half In Three Weeks

Category: Medical Marijuana | Posted on Sat, August, 31st 2013 by THCFinder
study-shows-cannabis-shrinks-tumorsA Harvard study from 2007 which remains the most comprehensive ever released on THC’s potential to combat tumors found that in just three weeks doses of THC were able to cut lung cancer tumor growth in half in mice subjects, and were able to reduce cancer lesions by even more.
 
For the study, Harvard researchers tested THC (delta-9-tetrahydrocannabinol, which is found naturally in cannabis) on cancer cells in labs, and followed that up by studying mice subjects.
 
The lab demonstration found that doses of THC inhibited growth and spread in the cancer cells; “When the cells are pretreated with THC, they have less EGFR stimulated invasion as measured by various in-vitro assays,” states Anju Preet, PhD, who was one of the researchers for the study.
 
Following the lab test, researchers dosed mice – which were implanted with human lung cancer cells – with THC, and found that in just three weeks, tumors were reduced in both size and weight by roughly 50% compared to a control group. According to Preet, cancer lesions on the lungs were also reduced – by nearly 60% – and there was as a significant reduction in “protein markers” associated with cancer progression.
 
Researchers predict that THC had such a positive effect on combating tumors because it activates molecules that arrest the cell cycle, and may also interfere with the processes of angiogenesis and vascularization, which lead to cancer growth.
 
Over 6 years since its original release, this study remains one of the most important cannabis-related studies ever released.
 

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