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Medical Marijuana

Activation Of Cannabinoid Receptors May Treat Alzheimers Disease

Category: Medical Marijuana | Posted on Sat, September, 7th 2013 by THCFinder
cannabis-helps-treat-alzheimersA new study published by the journal Neurobiology of Aging has found promising evidence to suggest that Alzheimer’s disease is significantly worsened by a deficiency in the body’s cannabinoid receptors, indicating that the disease could be treated with cannabis, which naturally activates these receptors.
 
For the study, researchers implanted mice with Alzheimer’s disease, and examined a control group compared to a group which was deficient in cannabinoid receptors. Researchers found that the mice which were deficient in a particular cannabinoid receptor “showed impaired learning and memory deficits” compared to the control group.
 
According to the study’s abstract, “The surviving mice showed a reduced amount of APP and its fragments suggesting a regulatory influence of CB1 on APP processing, which was confirmed by modulating CB1 expression in vitro”.
 
Researchers conclude that these “findings indicate that CB1 deficiency can worsen AD-related cognitive deficits and support a potential role of CB1 as a pharmacologic target.”
 
These findings help to confirm a study published recently in the journal Molecular and Cellular Neuroscience, which found that cannabis can slow, and potentially even cure Alzheimer’s disease.
 

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New Study Finds Cannabis May Provide Treatment For Skin Diseases

Category: Medical Marijuana | Posted on Fri, September, 6th 2013 by THCFinder
cannabis-good-for-skin-disesesA new study, recently published online in the British Journal of Pharmacology, details how cannabinoids can play a role in the treatment of skin diseases.
 
Researchers looked at the impact of phytocannabinoids (plant-derived cannabinoids, rather than synthetic counterparts) on epigenetic regulation of skin differentiation genes.
 
The study found that both cannabidiol (CBD) and cannabigerol (CBG), “significantly reduced the expression of all genes tested via increased DNA methylation for keratin 10 gene”.
 
The CBD was found to reduce keratin 10 mRNA through stimulating type-1 cannabinoid (CB1) receptors, while the CBG was found to act through a secondary method that did not engage the CB1 or CB2 receptors of keratinocytes (HaCaT cells). It was also revealed that cannabidiol increased global DNA methylation levels.
 
The study concludes that cannabis could act as a primary treatment for epidermal ailments:
 
“These findings identify the phytocannabinoids cannabidiol and cannabigerol as transcriptional repressors that can control cell proliferation and differentiation, suggesting (especially for cannabidiol) a possible exploitation as lead compounds to be used in the development of novel therapeutics for skin diseases.”
 
This report was conducted by researchers at the University of Teramo, the Campus Bio-Medico University and the Santa Lucia Foundation, all located in Italy.
 

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Medical marijuana patients ask review panel to add post-traumatic stress disorder to Michigan law

Category: Medical Marijuana | Posted on Fri, September, 6th 2013 by THCFinder
trying-to-get-ptsd-added-to-mi-rulesLANSING, MI -- Lillith Gwener survived sexual and physical abuse as a child, but she couldn't make it through a PG-13 movie this week without shaking and sobbing.
 
Gwener, 46, has lived most of her life with post-traumatic stress disorder, and her symptoms can be triggered by a variety of stimuli. Wednesday night, a violent scene in "The Butler" set her off.
 
"You're always in fight or flight," she said. "You're always afraid. Like me going to see this movie last night. I'm sitting in a movie and all of a sudden I'm shaking, I'm hyperventilating and I'm going through a pure anxiety attack."
 
Gwener was one of roughly 20 patients, activists and entrepreneurs who testified Thursday afternoon at a public meeting of the Michigan Marihuana Review Panel, which is considering a citizen petition to add PTSD to the list of debilitating conditions suitable for treatment under the state's voter-approved law.
 
The Holland resident is certified to use medical marijuana for chronic pain, but she said the medication also has proved effective for her PTSD and insomnia.
 
"It gives me a moment between the event -- the trigger -- and what my brain does. It lets me take that minute and realize, 'Hey, this is just a movie. I'm not under attack.'"
 

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Find Relief with GoldPens

Category: Medical Marijuana | Posted on Thu, September, 5th 2013 by THCFinder

tetra-labs-gold-pens

Need fast acting smokeless relief but cannot visit a dispensary? Now California medical cannabis patients can order GoldPens and other TetraLabs smoke-free products and get personal delivery anywhere in California.

 

GoldPen™ PureGold™ Personal Vaporizer.  Medicate anywhere discreetly. Get instant relief without inhaling smoke from burning plant material. Just press the button and inhale. Your GoldPen is assembled and ready to go. Cartridges are pre-loaded with 0.5g of PureGold for 100-200 puffs. Replacement cartridges are available at TetraLabs.com and dispensaries throughout California. Or save a few dollars by refilling your cartridge with a TetraLabs PureGold Squeeze Tube.

 

Enroll today in TetraLabs Patient Direct.

Get $20 off and free home delivery

on any order over $100.* A $40 value.

 

Order Discreetly and Save $40.  California medical cannabis patients can join the TetraLabs Collective and order smoke-free TetraLabs products online and our driver will deliver anywhere in California. And get $20 off plus free home delivery on any order over $100.* A $40 value. Also available in many California dispensaries. For a dispensary list, click here.

 

Enroll here with Coupon Code: THCFinder2

 

Four Smoke-Free Alternatives.  Just swallow a GoldCap™, and go about your business with all-day relief. Or use the faster-acting GoldMist™ Oral Spray as if it were a breath freshener. Or get instant relief with the GoldPen Personal vaporizer. Or use PureGold Squeeze Tubes to refill the GoldPen or other vaporizers.

 

Unrivaled Purity and Consistency.  TetraLabs produces pharmaceutical-grade medical cannabis products that contain the highest-purity, natural cannabinoids available. No other company in the industry offers our levels of quality, dependability and repeatability. GoldCaps contain only PureGold and grape seed oil. GoldMist contains only PureGold, grain alcohol and flavorings. GoldPen cartridges and PureGold Squeeze Tubes contain only ultra-pure natural cannabinoids with a touch of limonene. Crystal-clear contents mean you can see there’s no powdered cannabis, hashish, kif or hash oil. There are also no molds, pesticides, solvents, bacteria, toxins or other contaminants. That’s why our products are safe even for patients with suppressed immune systems.

 

Questions? Email info@tetralabs.com

 

*Offer expires 10-4-2013. One coupon per patient. California TetraLabs collective members only.


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Washington D.C. Medical Marijuana Dispensaries Discounting Meds For Poor People

Category: Medical Marijuana | Posted on Thu, September, 5th 2013 by THCFinder
wa-dc-to-give-discounts-to-poor-peopleA proposed law would make medical marijuana dispensaries in Washington, D.C. give 2% of their profits to a program to provide cannabis to the poor.
 
The Washington Times reports that, in addition to the profit tithe, “Under the regulatory proposal, dispensaries would give at least a 20 percent discount on marijuana to low-income people at or below 200 percent of the federal poverty level.” Cards issued to D.C.’s registered patients already indicate if their income level qualifies them for the discounted rate.
 
The goal is to make access to cannabis easier for those economically disadvantaged persons. Although safe access centers in other states may have individual policies regarding discounts for the poor, “This rule is totally unprecedented in the medical marijuana community,” said Alan St. Pierre, Executive Director for national NORML.
 
The District’s first dispensary, Capital City Care, charges from $380 – $440 per ounce of marijuana, according to the report. “Marijuana is overpriced because it’s overregulated, so a program for the poor is necessary,” Dan Riffle of the Marijuana Policy Project told the Times. “There’s this outdated hysteria surrounding marijuana, but it’s much safer than many other medications.”
 
The discount program is still in development and there are issues regarding reporting and collecting that have not been settled.
 

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Compounds In Cannabis Found To Reduce Nausea In New Study

Category: Medical Marijuana | Posted on Tue, September, 3rd 2013 by THCFinder
cannabis-naseuA new study published by the British Journal of Pharmacology and the National Institute of Health has found that THCV, and CBDV - two compounds found naturally in cannabis which aren’t psychoactive like THC – were both successful at reducing nausea in rat subjects.
 
For the study, researchers “evaluated two phytocannabinoids, cannabidivarin (CBDV) and Δ9 -tetrahydrocannabivarin (THCV) for their ability to produce these behavioural effects characteristic of CB1 receptor inverse agonism in rats.”
 
In doing so, researchers found that; “THC (2.5 and 10 mg kg-1 ), THCV (10 mg kg-1) and CBDV (200 mg kg-1 ) suppressed LiCl-induced conditioned gaping, suggesting anti-nausea potential.”
 
The study concludes; “The pattern of findings indicates that neither THCV nor CBDV produced a behavioural profile characteristic of CB1 receptor inverse agonists. As well, these compounds may have therapeutic potential in reducing nausea.”
 
This study indicates that it may be possible to use THCV or CBDV to help reduce nausea without bringing forth the psychoactive effects associated which THC, which may be seen as undesirable to some.
 
This research was funded in part by the Natural Sciences and Engineering Research Council of Canada.
 

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