Cannabis May Grow Stem Cells, Repair The Brain After Injury
Category: Medical Marijuana | Posted on Mon, December, 2nd 2013 by THCFinder
A new study being published in next month’s issue of the journal Biochemical Society Transactions, and published online early by the National Institute of Health, has found that the brain’s endocannabinoid system – which is activated through cannabis use – has neuroprotective and immunomodulatory capabilities, and may lead to the growth of stem cells.
“Activation of cannabinoid receptors suppresses chronic inflammatory responses through the attenuation of pro-inflammatory mediators”, states the study’s abstract. “Moreover, the endocannabinoid system directs cell fate specification of NSCs (neural stem cells) in the CNS (central nervous sytem)”.
According to researchers; “Pharmacological blockade of CB1 and/or CB2 cannabinoid receptors abolish or decrease NSC proliferation, indicating a critical role for both CB1 and CB2 receptors in the proliferation of NSC via IL-1 signalling pathways.”
They conclude; “Thus the endocannabinoid system, which has neuroprotective and immunomodulatory actions mediated by IL-1 signalling cascades in the brain, could assist the process of proliferation and differentiation of embryonic or adult NSCs, and this may be of therapeutic interest in the emerging field of brain repair.”
Read more: http://www.theweedblog.com
Chicago proposes tough rules on medical marijuana
Category: Medical Marijuana | Posted on Fri, November, 29th 2013 by THCFinder
November 27, 2013 (CHICAGO) -- Officials in Chicago have proposed strict regulations about where marijuana can be grown and dispensed in the city when it becomes legal in January.
Alderman Ed Burke and the city's Department of Planning and Development have been working on legislation in anticipation of a state law that will make Illinois the 20th state in the nation to allow medical marijuana. The measure must go to the full City Council for final approval.
The Chicago Sun-Times reports that the proposed legislation would only allow marijuana dispensaries and growing centers in manufacturing district. It also would require special use permits.
The measure would allow 22 cultivation centers in Chicago. It would prohibit them from opening within 2,500 feet of a school, day care center or residential area.
Strain Review; Afghani
Category: Medical Marijuana | Posted on Fri, November, 29th 2013 by THCFinder
Rainy days, snow storms, or just plain lazy days merit a strain that's going to make you feel... Well... Lazy, right? I have just the strain for that. The Afghani strain is not only extremely potent but gives the user and very heavy body high. Going far beyond couch lock, the Afghani strain will straight up knock you out if you smoke too much of it at one time.
Used mainly in patients with severe pain and insomnia, the Afghani strain makes the pain just go away... Or it makes you high enough to just totally forget about it. It helps with pain, stress, anxiety, and insomnia so it has a wide range of uses among illnesses. Play sports? Get pulled muscles a lot? Pairing this weed with an Icy Hot Patch is sure to help relieve any stressful injury.
With almost no abnormal negatives (other than the always present dry mouth), Afghani should at least grace your piece at least once. Whether you prefer to use it as a wake and bake, a replacement for your insomnia medicine, or just to unwind, I strongly recommend this strain.
See more strains here: http://www.thcfinder.com/strains/
Indoor Vs Outdoor Cannabis
Category: Medical Marijuana | Posted on Thu, November, 28th 2013 by THCFinder
The way that weed is grown greatly effects the end result. If the plant isn't raised correctly or fed the right way, it's not going to produce quality smoking buds. Not only that but there is indoor grown cannabis and outdoor grown. Surprisingly, the two have really different qualities about them. Since the conditions that they're growing in are so different, the buds produced vary in size, shape, and color.
Most people prefer to grow indoors. There are more variables that can be controlled, such as light time and temperature, not to mention pest control is far easier. You can also grow year round with indoor. For a lot of people, winter gets too harsh to be able to grow outdoors. Indoor plants can be grown as long as they need to be to get the highest yield possible. On the downside, growing indoors can be extremely pricey. Between the electricity bills and the cost of the supplies, growing indoors requires a substantial down payment if you're looking to get a good grow started.
Outdoor weed always carries the smell of the outside with it. Even if it's faint, one can usually tell what plant surrounded the cannabis as it grew. Not to mention your plants have unlimited amounts of space to grow, allowing them to reach tree height if they're allowed to. The sun is also the best lighting that a plant get. There is no bulb that can compare to sunlight and therefore, the plants get what they need from the sun. Unfortunately, you're at the mercy of the elements and hungry animals. Deer are notorious for eating pot plants. What also much be taken in to account is thieves. If someone discovers your grow spot, you could end up with no plants at all.
Most of the time, the weed depends on geography. Warmer climates will obviously have primarily outdoor grows. Colder places will usually have a grow outside during the warmer months but continue to grow indoors year round, which actually turns out pretty good. Or a warm climate with both indoor and outdoor. Whatever the case is, if you're growing, props to you! It's a difficult task to grow cannabis well and you hard workers should know that you're appreciated! And to the smokers, enjoy whatever weed you like smoking! Stay high!
Hershey 3-year-old's condition makes a case for medical marijuana
Category: Medical Marijuana | Posted on Wed, November, 27th 2013 by THCFinder
If Pennsylvania legislators would heed the plight of 3-year-old Hershey resident Garrett Brann, they would agree to take a more rational approach toward the medical use of marijuana.
Garrett has Dravet Syndrome, a severe form of epilepsy that starts in infancy. The disease wracks his body with seizures, as if random jolts of electricity are repeatedly shooting through him.
With his debilitating condition, Garrett frequently falls and can’t feed himself. His family has tried roughly 10 different types of anti-seizure drugs.
One treatment might help, but it is illegal in Pennsylvania.
“Charlotte’s Web” is an oil derived from marijuana plants. It comes from a benign strain of marijuana, one that has almost no THC, the chemical that gives users the euphoric “high.” Patients take the oil with food, not by smoking.
ther families whose children suffer serious seizures have used the oil extract, with good results. Dr. Sanjay Gupta, CNN’s chief medical correspondent, documented how marijuana is helping treat a child with chronic seizures in Colorado, where medical marijuana is legal.
Garrett’s mother told WITF’s Radio SmartTalk Monday she didn’t know if the marijuana oil extract will help her son. But the family would like to give it a try and is considering a move to Colorado.
Garrett, his family and others facing similar medical challenges deserve to have every possible tool that might help them, right here in Pennsylvania.
Read more: http://www.pennlive.com
Study shows marijuana's potential for treating autoimmune disorders
Category: Medical Marijuana | Posted on Tue, November, 26th 2013 by THCFinder
A new study from researchers at the University of South Carolina provides evidence that THC (tetrahydrocannabinol), a principal ingredient in marijuana, may be beneficial in treating those with autoimmune disorders.
The study, published in the Journal of Biological Chemistry, is the first to explore how tiny, yet powerful molecules called microRNAs are influenced by THC. MicroRNAs are a recently discovered class of non-coding RNAs that play a pivotal role in the regulation of gene expression. The ability to alter microRNA expression could hold the key to successful treatments for a whole host of autoimmune diseases, including arthritis, multiple sclerosis and type 1 diabetes.
The study was performed by researchers from USC's School of Medicine by injecting laboratory mice with THC and analyzing 609 microRNAs. The researchers identified 13 unique microRNAs that were highly altered by THC.
MicroRNAs have profound effects on the immune system, acting as 'brakes' that target more than 60 percent of all gene expression. Since microRNAs normally suppress the expression of genes, when a microRNA is overexpressed, the affected gene gets silenced. But when microRNA is turned off, the affected gene is expressed at an elevated level.
The authors also studied how a specific microRNA—miRNA-690—that was highly overexpressed in response to THC functionally targets an important protein called C/EBPα. This molecule in turn triggers unique cells known as MDSC that suppress inflammation. When the researchers successfully knocked down miRNA-690, the effect of THC was reversed.
Read more: http://medicalxpress.com
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