Marijuana May Deflect Obesity

Category: News | Posted on Tue, July, 10th 2012 by THCFinder
Cannabis seems to have many different allures. It can produce a “high.” It can give the feeling of munchies. Now, it can possibly help combat obesity. Scientists recently revealed that they found two compounds from cannabis leaves that could up the total energy that the body burns.
Previous studies of two specific compounds demonstrated that they could be used to treat type-two diabetes. The compounds were also discovered to have the ability to reduce cholesterol levels in the blood stream and decrease fat in important organs such as the liver. With the aim of treating patients who have “metabolic syndrome,” the researchers are currently conducting clinical trials in 200 patients with the drug. With “metabolic syndrome,” diabetes, high blood pressure, and obesity combine to heighten the risk of heart disease and stroke in patients.
“We are conducting four Phase 2a clinical trials and we expect some results later this year,” commented Dr. Steph Wright, director of research and development at GW Pharmaceuticals, in a Telegraph article. “The results in animal models have been very encouraging. We are interested in how these drugs effect the fat distribution and utilization in the body as a treatment for metabolic diseases… Humans have been using these plants for thousands of years so we have quite a lot of experience of the chemicals in the plants.”
GW Pharmaceuticals was given a license to grow cannabis in greenhouses that were specially constructed for project. The company produces cannabis plants that have a number of cannabinoids, which are varied compounds of cannabis. They are already working on creating drugs that can assist in treating epilepsy and multiple sclerosis. Interesting enough, when the scientists studied two specific compounds, THCV and cannabioidoil, they found that they had the ability to suppress appetite but the effect lasted for a short amount of time. Upon further examination, the investigators discovered that the compounds could influence the fat level in the body as well as its effects to the hormone insulin.
Likewise, the studies of the compounds in mice showed that they increased the metabolism of the animals, causing decreased levels of fat in livers and minimized levels of cholesterol in the blood stream. In particular, THCV showed the ability of boosting the animals’ sensitivity to insulin but also shielding the insulin-producing cells. With these actions, the cells were able to work at a longer and more durable pace.
The researchers hope that the findings will help in the development of treatments for obesity-related illnesses and type-two diabetes.
“Overall, it seems these molecules increase energy expenditure in the cells of the body by increasing the metabolism,” noted Professor Mike Cawthorne, director of metabolic research at the University of Buckingham and animal studies researcher, in the Telegraph article.


Oxycontin for Kids

Category: News | Posted on Mon, July, 9th 2012 by THCFinder

Many will tell you that parents allowing their children to ingest medical cannabis is a very controversial thing and should not be allowed without extensive testing.


Those at the FDA would certainly look down their nose at such dangerous practices. How dare you use a non-toxic plant to help children?


The FDA and the generous folks at Purdue Pharma have a better idea: Oxycontin for kids!


That’s right, the highly addictive painkiller is currently being tested on children ages 6 and up. Worried that its patent for the drug is expiring soon, Purdue Pharma is seeking another six months from the DEA – six months that are worth about $1.4 billion to the company.


To get those 6 months, the company must prove to the FDA that the drug has use…among children.


According to The Young Turks, the company “insists it is conducting the trials to ensure the safety of children currently being prescribed OxyContin ‘off-label’ by doctors, some, including three physicians involved in the trials, said the company is more concerned about the impending expiration of the drug's patent, and is hoping to receive a six-month extension from the FDA.”


How much more money can be made off of Oxy if kids get hooked on it? The possibilities are endless when it comes to greed and death.





Scientific Review says Cannabis Schedule I Classification Is Not Tenable

Category: News | Posted on Thu, July, 5th 2012 by THCFinder

A new scientific review in The Open Neurology Journal questions cannabis’ place as a Schedule I drug under the federal Controlled Substances Act.


Reviewers from the University of California at San Diego and the University of California, Davis went over several recent clinical trials on the safety and effectiveness of cannabis.


“Evidence is accumulating that cannabinoids may be useful medicine for certain indications,” the review concluded. “Control of nausea and vomiting and the promotion of weight gain in chronic inanition are already licensed uses of oral THC (dronabinol capsules). Recent research indicates that cannabis may also be effective in the treatment of painful peripheral neuropathy and muscle spasticity from conditions such as multiple sclerosis. Other indications have been proposed, but adequate clinical trials have not been conducted.


“… The classification of marijuana as a Schedule I drug as well as the continuing controversy as to whether or not cannabis is of medical value are obstacles to medical progress in this area. Based on evidence currently available the Schedule I classification is not tenable; it is not accurate that cannabis has no medical value, or that information on safety is lacking. It is true cannabis has some abuse potential, but its profile more closely resembles drugs in Schedule III (where codeine and dronabinol are listed). The continuing conflict between scientific evidence and political ideology will hopefully be reconciled in a judicious manner.”


Dr. Igor Grant was the lead author of the review, and he is director of the Center for Medicinal Cannabis Research, which has done several FDA-approved ‘gold standard’ clinical trials on cannabis.


The fact is the federal government is the only entity left holding on to this ridiculous fantasy that cannabis has no medical value. And in the meantime they are hurting millions of patients by restricting access and research.




Company in Israel Develops Cannabis Plant without the High

Category: News | Posted on Thu, July, 5th 2012 by THCFinder

Tikun Olam, a company in Israel, has developed a marijuana plant that has no THC in it. For some medical marijuana patients, the “high” that comes from THC is not needed, or even wanted. It depends on their ailment(s).


While there are over 60 cannabinoids in the marijuana plant, one in particular has been shown to have multiple medical properties, including an anti-inflammatory effect. That chemical is Cannabidiol, or CBD.


"CBD plants are available in different forms all over the world," said Zack Klein, head of development at Tikun Olam, adding that the company's plant is free of THC and very high in CBD. He says they have developed Avidekel, a cannabis strain that contains 15.8 % CBD and only traces of THC, less than 1%.


According to Raphael Mechoulam, a professor of medicinal chemistry at the Hebrew University in Jerusalem, this is the first non-THC strain developed in Israel. "It is possible that (Avidekel's) CBD to THC ratio is the highest among medical marijuana companies in the world, but the industry is not very organized, so one cannot keep exact track of what each company is doing," he said.


Ruth Gallily of the Hebrew University who works for the company and has been studying CBD for more than 12 years, says, "The cannabis plant, enriched with CBD, can be used for treating diseases like rheumatoid arthritis, colitis, liver inflammation, heart disease and diabetes."


Marijuana with no THC can be very helpful to people who have a lot of stuff to do during the day, but don’t want to be high or in pain.


Cannabis is an incredibly versatile plant, and we have only seen part of what it can do. If the government would just get out of the way, marijuana could be helping so many people.




Colombia Decriminalizes Cocaine and Marijuana, As Latin American Momentum for Drug Policy Reform Continues

Category: News | Posted on Mon, July, 2nd 2012 by THCFinder
Colombia's Constitutional Court Friday approved the government's proposal to decriminalize the possession of small amounts of cocaine and marijuana for personal use. Anyone caught with less than 20 grams of marijuana or one gram of cocaine for personal use may receive physical or psychological treatment depending on their state of consumption, but may not be prosecuted or detained, the court ruled.
Colombia's move is part of a growing trend in Latin America. After decades of being brutalized by the U.S. government's failed prohibitionist drug policies, Latin American leaders are saying "enough is enough."
Last week, the government of Uruguay announced that it will submit a proposal to legalize marijuana under government-controlled regulation and sale, making it the first country in the world where the state would sell marijuana directly to its citizens. The proposal was drafted by Uruguayan President José Mujica and his staff and requires parliamentary approval before being enacted.


Medical Marijuana Businessman in Montana Suing a Lot of People

Category: News | Posted on Fri, June, 29th 2012 by THCFinder

Jason Christ, who gained a measure of fame in Montana a few years ago with his traveling, one-day medical marijuana clinics, is now embroiled in more than a dozen lawsuits with everyone from the Missoula County Attorney’s Office to his former partners and competitors.


Jason filed 13 lawsuits in 2011, and has been involved in more than 1,300 pleadings in 25 civil and one criminal case. “The court called plaintiff a ‘difficult litigant,’ based solely on the number of pleadings, not on the merits of those papers,” read court documents.


In court papers Christ says he is beset on all sides by law enforcement and officials and the city and county have lost him income, “affected his bodily functions” and forced him to camp “down a vast network of unimproved dirt roads.”


Mr. Christ also has attempted to gain redress from the state’s Governor and Attorney General, all to no avail. “The AG has never returned the plaintiff’s calls,” says a court document.


Missoula County Attorney Fred Van Valkenburg said he assumes the court will dismiss the lawsuit “at some point.” It names as one defendant a “Paul” Van Valkenburg, which the county attorney said he believes is a reference to himself and “part of his (Christ’s) ineptness.”


“Basically, we disagree with all of the allegations in his complaint,” Van Valkenburg said. “And it’s just part of what we have to deal with in dealing with Mr. Christ.”


Christ is also going to trial in October for allegedly threatened employees of Verizon wireless. According to the complaint filed against him, Christ said he “was going to come down there and ‘bomb the (expletive) store.’”


Christ also says that since he is not allowed to have weapons, he is left to the mercy of the animals in the woods where he lives.


Christ wants for $1.5 million in lost business, $50 million in punitive damages, $34,000 for legal defense against frivolous lawsuits, and $26,850 as payment for defending himself.


An odd and interesting story, to say the least.





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